Is the Nanotax clinical trial right for you?

We are now conducting research to test Nanotax®, a new chemotherapy drug for patients who have been diagnosed with a peritoneal cancer, including ovarian or other gynecological, pancreatic or colorectal cancers, as well as mesothelioma. Nanotax is being evaluated to see if it can reduce or eliminate chemotherapy’s serious side effects.

If you have been diagnosed with a peritoneal cancer and have not responded well to standard treatments, you may be eligible to participate in this phase I clinical trial.

Testing an alternative to traditional chemotherapy

Traditional chemotherapy, with Paclitaxel, often makes people very sick with side effects, such as hair loss, low blood counts, nausea and allergic reactions. Because Nanotax is reformulated and doesn't contain the toxic properties that cause these side effects, we want to see if it will reduce or eliminate them. This phase I, first-in-humans clinical trial will determine the safest dosage and side effects of Nanotax.

This trial also studies the way the drug is delivered. Nanotax is delivered into the abdomen, rather than intravenously. Early studies in mice indicate this delivery method allows the drug to stay in the peritoneal cavity where the cancer is, rather than be absorbed throughout the body.

Where did Nanotax come from?

Nanotax is the first bench-to-bedside drug developed and tested at The University of Kansas Cancer Center. It was formulated by our scientists, and it is now being studied with patients.

Which patients can participate?

You may be eligible if you are at least 18 years old and have been diagnosed with a peritoneal cancer (tumors confined to the peritoneal cavity, predominantly ovarian or other gynecological, pancreatic or colorectal cancers, or mesothelioma).

Only those who have not responded to standard treatment and have no further treatment options can join the study. Participants must meet specific criteria and go through a screening. Timing of your treatment will depend on the current progress of the study.

Where is treatment provided?

Treatment is provided at the Richard and Annette Bloch Cancer Care Pavilion in Westwood, Kansas, and outreach locations in Wichita.

How is care provided?

Care for patients in a clinical trial is provided in the same way standard treatment is provided. Your physicians, nurses and other health professionals will provide care, keep you informed about your treatment and measure your progress. To ensure reliable results, it's important for you to follow the care team’s instructions.

Learn more details about the Nanotax clinical trial.