Lauren Nye, MD

Dr. Lauren Nye is certified by the American Board of Internal Medicine with a subcertification in medical oncology. She completed a fellowship at Northwestern Memorial Hospital. She earned her medical degree from the University of Kansas School of Medicine and completed her residency at Northwestern Memorial Hospital. Dr. Nye specializes in the management of the continuum of breast cancer - from breast cancer prevention to treatment of breast cancer to improving survivorship. She wants to guide patient’s through their individual journey.
She sees patients in her High Risk Breast Clinic who are at an increased risk for breast cancer which can include having a family history of breast cancer, carrying a genetic mutation increasing the risk of breast cancer or having a prior breast biopsy that elevates ones risk for breast cancer. She also sees patients in her Breast Oncology Clinic who have a diagnosis of breast cancer and has a special interest in the management of breast cancer diagnosed during pregnancy.

Dr. Nye’s areas of research include breast cancer prevention and survivorship with current projects focusing on prevention in young women at high risk for breast cancer who are still considering pregnancy, for postmenopausal women who are experiencing hot flashes and weight loss interventions in women at high risk, genetic mutation carriers and breast cancer survivors. She also works with the breast cancer team to design and ensure clinical trials are available to our breast cancer patients requiring treatment.

Benign Breast Disease

Breast Cancer

Breast Cancer Outcomes After Diagnosis of Hormone-positive Breast Cancer and Subsequent Pregnancy in the Tamoxifen Era.

Clinical and Biomarker Results from Phase I/II Study of P13K Inhibitor Alpellsib plus Nab-Paclitaxel in HER2-Negative Metastatic Breast Cancer

Diagnostic and Treatment Considerations When Newly Diagnosed Breast Cancer Coincides with Pregnancy: A Case Report and Review of Literature

Ectopic Production of B--hCG and Loss of P16 as a Predictor of Outcome in Patients with Newly Diagnosed Osteosarcoma

Effect of Bazedoxifene and Conjugated Estrogen (Duavee) on Breast Cancer Risk Biomarkers in High-Risk Women: A Pilot Study.

Fixed dose, dose-dense capecitabine in metastatic breast cancer.

Impact of Germline BRCA Mutation Status on Survival in Women with Metastatic Triple Negative Breast Cancer

Integrating Breast Cancer Risk Management into Primary Care

Pilot study of the combination of bazedoxifene and conjugated estrogen to modulate risk biomarkers in women with hot flashes at increased risk for breast cancer

Randomized Phase II Trial of Anthracycline-free and Anthracycline-containing Neoadjuvant Carboplatin Chemotherapy Regimens in Stage I-III Triple-Negative Breast Cancer (NEOSTOP)

Rapid Escalation of High-Volume Exercise During Caloric Restriction; Change in Visceral Adipose Tissue and Adipocytokines in Obese Sedentary Breast Cancer Survivors

Results of randomized phase II trial of neoadjuvant carboplatin plus docetaxel or carboplatin plus paclitaxel followed by AC in stage I-III triple-negative breast cancer (NCT02413320).

A Phase I Study of Palbociclib, Letrozole and TDM1 in Trastuzumab Reffractory Estrogen Receptor Positive and HER2 Positive Metastatic Breast Cancer

Analysis of Breast and Stool Microbiome in Premenopausal Women at High Risk for Breast Cancer

Biomarker-Based Phase IIB Trial of (Bazedoxifene-Conjugated Estrogen) to Reduce Risk for Breast Cancer

Efficacy of Point of Service Testing in Breast Cancer (E-POST BC)

Feasibility of a Translational Mouse and Human Model to Identify a Signature of Non-response in DCIS

Feasibility Study of Moderate Dose Omega-3 Fatty Acid Supplementation in Premenopausal Women at High Risk for Breast Cancer and Considering Future Pregnancy

Increasing Rates of BRCA Testing in Patients with Breast Cancer

Pilot Study of Effects of Duavee on Imaging and Blood Biomarkers in Women with Menopausal Symptoms at Increased risk for Breast Cancere

POLARIS: Palbociclib (IBRANCE) in Hormone Receptor Positive Advanced Breast Cancer; A Prospective Multi-center Non-Interventional Study

Project BRA: Project ECHO Breast Cancer Risk Assessment

Efficacy of Point of Service Testing in Metastatic Breast Cancer (E-POST-MBC)

Testing for Atypia in Random Periareolar Fine Needle Aspiration (RPFNA) Cytology After 12 Months Metformin (1,1-Dimethyibiguanide Hyrochloride) Chemoprevention Versus Placebo Control in Premenopausal Women