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A Phase Ib/II Open-Label Study of APVO436 in Combination with Venetoclax and Azacitidine in Patients with Newly Diagnosed Acute Myeloid Leukemia AML
Study Type: Treatment
Phase: I/II
NCTID: NCT06634394
Principal Investigator:
Tara Lin
A Prospective Randomized, Double-blind, Placebo-controlled, Multi-center Phase III Study to Evaluate the Efficacy and Safety of Mocravimod as an Adjunctive and Maintenance Treatment in Adult Acute Myeloid Leukemia AML Patients Undergoing Allogeneic Hematopoietic Cell Transplantation HCT
Study Type: Treatment
Phase: III
NCTID: NCT05429632
Principal Investigator:
Haitham Abdelhakim
A Measurable Residual Disease MRD Focused, Phase II Study of Venetoclax Plus Chemotherapy for Newly Diagnosed Younger Patients with Intermediate Risk Acute Myeloid Leukemia: A Tier 1 MYELOMATCH SubStudy
Study Type: Treatment
Phase: II
NCTID: NCT05554393
Principal Investigator:
Heather Male
A Randomized Phase II Study of Venetoclax and HMA-Based Therapies for the Treatment of Older and Unfit Adults with Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia AML: A MyeloMATCH Treatment Trial
Study Type: Treatment
Phase: II
NCTID: NCT06317649
Principal Investigator:
Jesus Gonzalez Lugo
Phase I study of venetoclax/azacitidine or venetoclax in combination with ziftomenib KO-539 or standard induction cytarabine/daunorubicin 7+3 chemotherapy in combination with ziftomenib for the treatment of patients with acute myeloid leukemia
Study Type: Treatment
Phase: I
NCTID: NCT05735184
Principal Investigator:
Tara Lin
A PHASE 1 STUDY OF REVUMENIB, AZACITIDINE, AND VENETOCLAX AND IN PEDIATRIC AND YOUNG ADULT PATIENTS WITH REFRACTORY OR RELAPSED ACUTE MYELOID LEUKEMIA
Study Type: Treatment
Phase: I
NCTID: NCT06177067
Principal Investigator:
Keith August
Phase I Study to Determine the Safety and Tolerability of Ziftomenib Combinations for the Treatment of KMT2A-rearranged or NPM1-mutant Relapsed/Refractory Acute Myeloid Leukemia
Study Type: Treatment
Phase: I
NCTID: NCT06001788
Principal Investigator:
Tara Lin
A Phase Ib Study of Menin Inhibitor SNDX-5613 in Combination with Daunorubicin and Cytarabine in Newly Diagnosed Patients with Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged Disease or NUP98 Alterations
Study Type: Treatment
Phase: I
NCTID: NCT05886049
Principal Investigator:
Jesus Gonzalez Lugo
A Randomized Phase II Trial of ASTX727 and Venetoclax Compared with ASTX727, Venetoclax, and Enasidenib for Newly Diagnosed Older Adults with IDH2Mutant Acute Myeloid Leukemia: A MyeloMATCH Substudy
Study Type: Treatment
Phase: II
NCTID: NCT06672146
Principal Investigator:
Kenneth Byrd
A Phase 1 Study of SEA-CD70 Monotherapy or Combination with Azacitideine in Subjects with Myeloid Malignancies
Study Type: Treatment
Phase: I
NCTID: NCT04227847
Principal Investigator:
Abdulraheem Yacoub