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A Phase 1, Open-Label, Dose-Escalation Study of Olaratumab as a Single Agent and in Combination With Doxorubicin, Vincristine/Irinotecan, or High-Dose Ifosfamide in Pediatric Patients With Relapsed or Refractory Solid Tumors
Study Type: Treatment
Phase: I
NCTID: NCT02677116
Principal Investigator:
Expanded Access Program for belantamab mafodotin in Patients with Relapsed/Refractory Multiple Myeloma who are Refractory to a Proteasome Inhibitor, and an Immunomodulatory Agent, and an Anti-CD38 Antibody
A Phase III, Randomized, Controlled, Multicenter, Open-label Study to Compare Tivozanib in Combination with Nivolumab to Tivozanib Monotherapy in Subjects with Renal Cell Carcinoma Who Have Progressed Following One or Two Lines of Therapy Where One Line has an Immune Checkpoint Inhibitor 257305
Study Type: Treatment
Phase: III
NCTID: NCT04987203
Principal Investigator:
Elizabeth Wulff-Burchfield
MATCH Treatment Subprotocol H: Phase II Study of Dabrafenib and Trametinib in Patients with Tumors with BRAF V600E or V600K Mutations Excluding Melanoma and Thyroid Cancer
Study Type: Treatment
Phase: II
NCTID: NCT02465060
Principal Investigator:
Benjamin Powers
A Phase II Study of Sotorasib AMG 510 in Participants with Previously Treated Stage IV or Recurrent KRAS G12C Mutated Non-Squamous Non-Small Cell Lung Cancer ECOG-ACRIN LUNG-MAP SUB-STUDY
Risk-Based, Response-Adapted, Phase II Open-Label Trial of Nivolumab + Brentuximab Vedotin N + BV For Children, Adolescents, and Young Adults with Relapsed/Refractory R/R CD30 + Classic Hodgkin Lymphoma Chl After Failure of First-Line Therapy, Followed By Brentuximab + Bendamustine BV + B for Participants with a Suboptimal Response
Study Type: Treatment
Phase: II
NCTID: NCT02927769
Principal Investigator:
Kevin Ginn
A Phase IB/II Open-Label Trial of Tisotumab Vedotin HuMax-TF-ADC Monotherapy and in Combination with Other Agents in Subjects with Recurrent or Stage IVB Cervical Cancer
A Multi-Center Study Of Non-Invasive Colorectal Cancer Evaluation In Cystic Fibrosis NICE-CF
Study Type: Supportive Care
Phase: N/A
NCTID: NCT05362344
Principal Investigator:
Joel Mermis
A Phase III Randomized, Placebo-controlled, Double-blind Study of Niraparib in Combination with Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Subjects with Metastatic Prostate Cancer
Study Type: Treatment
Phase: III
NCTID: NCT03748641
Principal Investigator:
Elizabeth Wulff-Burchfield
Phase II Trial of Eflornithine/DFMO as Maintenance Therapy for Molecular High Risk/Very High Risk and Relapsed/Refractory Medulloblastoma
Study Type: Treatment
Phase: II
NCTID: NCT04696029
Principal Investigator:
Kevin Ginn