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A Phase II Randomized Controlled Trial of Neoadjuvant Pembrolizumab with Radiotherapy and Adjuvant Pembrolizumab in Patients with High-Risk, Localized Soft Tissue Sarcoma of the Extremity
Study Type: Treatment
Phase: II
NCTID: NCT03092323
Principal Investigator:
Benjamin Powers
A Phase 3, Randomized, Adaptive Study Comparing the Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease in Adult and Pediatric Patients Undergoing Hematopoietic Stem Cell Transplant
Study Type: Prevention
Phase: III
NCTID: NCT02851407
Principal Investigator:
Rakesh Goyal
Brightline-4: A Phase III open-label, single-arm, multi-center study to assess the safety and efficacy of brigimadlin BI 907828 treatment in patients with treatment-na�ve or pre-treated advanced dedifferentiated liposarcoma
Study Type: Treatment
Phase: III
NCTID: NCT06058793
Principal Investigator:
Benjamin Powers
Single Person IND for the Use of TK216 in a patient with metastatic Ewing sarcoma
Study Type: Treatment
Phase: N/A
NCTID: NCT00000000
Principal Investigator:
Benjamin Powers
A Phase 2, Multicenter, Open-label Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Subjects With Relapsed/Refractory Rhabdomyosarcoma RMS, Non-rhabdomyosarcoma Soft Tissue Sarcoma NRSTS and Ewing Sarcoma EWS
Study Type: Treatment
Phase: II
NCTID: NCT03441360
Principal Investigator:
Kevin Ginn
Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone: A Prospective Randomized Controlled Trial
Study Type: Treatment
Phase: III
NCTID: NCT03295981
Principal Investigator:
Kyle Sweeney
Randomized Phase II Trial Evaluation the Addition of the IGF-1R Monoclonal Antibody Receptor Ganitumab to Multiagent Chemotherapy for Patients with Newly Diagnosed Metastatic Ewing Sarcoma
Study Type: Treatment
Phase: II
NCTID: NCT02306161
Principal Investigator:
A Phase 2 Study of DS-8201a NSC 807708 in Adolescents, or Young Adults with Recurrent HER2+ Osteosarcoma
Study Type: Treatment
Phase: II
NCTID: NCT04616560
Principal Investigator:
Kevin Ginn
A Multicenter, Randomized, Placebo-controlled, Double-blind Study of DCC-3014 to Assess the Efficacy and Safety in Patients with Tenosynovial Giant Cell Tumor
Study Type: Treatment
Phase: III
NCTID: NCT05059262
Principal Investigator:
Benjamin Powers
A Randomized Phase III Trial of Vinorelbine, Dactinomycin, and Cyclophosphamide VINO-AC Plus Maintenance Chemotherapy with Vinorelbine and Oral Cyclophosphamide VINO-CPO vs Vincristine, Dactinomycin and Cyclophosphamide VAC plus VINO-CPO Maintenance in Patients with High Risk Rhabdomyosarcoma HR-RMS
Study Type: Treatment
Phase: III
NCTID: NCT04994132
Principal Investigator:
Keith August