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Selective Use of Observation After Lumpectomy and Sentinel Lymph Node Biopsy in Her-2 Positive Patients with Pathologic Complete Response to Neoadjuvant Chemotherapy
Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers in Women with Obesity and Other Risk Factors for Breast Cancer
Study Type: Prevention
Phase: Feasibility/Pilot
NCTID: NCT06485089
Principal Investigator:
Carol Fabian
A Phase I/II Trial Evaluating the Safety and Efficacy of Eribulin in Combination with Copanlisib in Patients with Metastatic Triple Negative Breast Cancer
Phase III Randomized Trial of Hypofractionated Post mastectomy Radiation With Breast Reconstruction
Randomized Open-Label Trial of Dose Dense, Fixed Dose Capecitabine Compared to Standard Dose Capecitabine in Metastatic Breast Cancer and Advanced/Metastatic GI Cancers
Randomized, Double-Blind, Phase III Study of Tucatinib or Placebo in Combination with Ado-Trastuzumab Emtansine T-DM1 For Subjects with Unresectable Locally-Advanced or Metastatic HER2+ Breast Cancer
INT23-14-01, Refining Tamoxifen Dose for Premenopausal Breast Cancer Risk Reduction RENAISSANCE: A Phase II Single Arm Trial
Study Type: Prevention
Phase: II
NCTID: NCT06184750
Principal Investigator:
Carol Fabian
OPTIMICE-PCR: De-Escalation Of Therapy In Early-Stage TNBC Patients Who Achieve PCR After Neoadjuvant Chemotherapy With Checkpoint Inhibitor Therapy
A Phase III Study That Will Evaluate The Safety And Efficacy Of The Study Drug A Reversible Dual Inhibitor That Selectively Targets Phosphoinositide 3-Kinase PI3K And Mammalian Target Of Rapamycin Mtor In Patients With HR+/HER2- Locally Advanced Or Metastatic Breast Cancer Who Have Progressed On Or After Treatment With A CDK 4/6 Inhibitor
Study Type: Treatment
Phase: III
NCTID: NCT05501886
Principal Investigator:
Anne O'Dea