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Randomized Phase III Trial of Pembrolizumab vs. Pembrolizumab/Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma with Platinum Refractory Disease.
Study Type: Treatment
Phase: III
NCTID: NCT06589804
Principal Investigator:
Prakash Neupane
Phase 1b Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Repeated Doses of DB-020 in Patients Receiving Cisplatin
A Randomized Phase II/III Trial of De-Intensified Radiation Therapy for Patients with Early-Stage, P16-Positive, Non-Smoking Associated Oropharyngeal Cancer
Study Type: Treatment
Phase: II/III
NCTID: NCT03952585
Principal Investigator:
Chris Lominska
A Phase III, Randomized, Open-Label, Multi-Center, Global Study of Volrustomig MEDI5752 as Sequential Therapy Versus Observation in Participants with Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma, Who Have Not Progressed Following Definitive Concurrent Chemoradiotherapy eVOLVE-HNSCC
A Phase III Randomized Placebo-Controlled Double-Blind Clinical Study of Pembrolizumab Mk-3475 With or Without Lenvatinib E7080/Mk-7902 to Evaluate the Safety and Efficacy of Pembrolizumab and Lenvatinib as 1L Intervention in a PD-L1 Selected Population of Participants with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma R/M HNSCC LEAP-010
Phase I/Ib Study of AKT Inhibitor Ipatasertib with Chemoradiation for Locally Advanced Head and Neck Cancer
Study Type: Treatment
Phase: I
NCTID: NCT05172245
Principal Investigator:
Chris Lominska