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Stopping Tyrosine Kinase Inhibitors TKI to Assess Treatment-Free Remission TFR in Pediatric Chronic Myeloid Leukemia - Chronic Phase CML-CP
Study Type: Treatment
Phase: Feasibility/Pilot
NCTID: NCT03817398
Principal Investigator:
Keith August
A Phase I/II study of Bosutinib in pediatric patients with newly diagnosed chronic phase or resistant/intolerant Ph+ Chronic Myeloid Leukemia
Study Type: Treatment
Phase: I/II
NCTID: NCT04258943
Principal Investigator:
Keith August
A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzumab Ozogamicin a Conjugated Anti-CD22 Monoclonal Antibody to Frontline Therapy in Young Adults Ages 18-39 Years with Newly Diagnosed Precursor B-Cell ALL
A Randomized Phase II/III Study of Conventional Chemotherapy +/- Uproleselan GMI-1271 in Older Adults with Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy
A Phase I, Open-Label, Multicenter Study of INCB160058 in Participants With Myeloproliferative Neoplasms
Study Type: Treatment
Phase: I
NCTID: NCT06313593
Principal Investigator:
Abdulraheem Yacoub
A Pilot Study of Targeted Daunorubicin Dosing to Overcome Chemotherapeutic Resistance in Children with Relapsed or Refractory Acute Leukemia
Study Type: Treatment
Phase: Feasibility/Pilot
NCTID: NCT04562792
Principal Investigator:
Chandni Dargan
International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Ph+ALL Testing Imatinib in Combination with Two Different Cytotoxic Chemotherapy Backbones
Study Type: Treatment
Phase: III
NCTID: NCT03007147
Principal Investigator:
Keith August
A Phase I Study to Evaluate the Safety and Pharmacokinetic Profiles of CB-5339 in Participants with Relapsed/Refractory Acute Myeloid Leukemia, Intermediate or Higher-Risk Myelodysplastic Syndromes, bcr-abl negative Myeloproliferative, Myelodysplastic/Myeloproliferative Neoplasms and Multiple Myeloma
A Phase I/II Study of Oral LOXO-305 in Patients with Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma CLL/SLL or Non-Hodgkin Lymphoma NHL
Study Type: Treatment
Phase: I/II
NCTID: NCT03740529
Principal Investigator:
Marc Hoffmann
A Phase III, Randomized, Open-Label Study Evaluating the Safety and Efficacy of Magrolimab in Combination with Azacitidine versus Physician?s Choice of Venetoclax in Combination with Azacitidine or Intensive Chemotherapy in Previously Untreated Patients with TP53 Mutant Acute Myeloid Leukemia.
Study Type: Treatment
Phase: III
NCTID: NCT04778397
Principal Investigator:
Jesus Gonzalez Lugo