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A Phase Ib Study of Menin Inhibitor SNDX-5613 in Combination with Daunorubicin and Cytarabine in Newly Diagnosed Patients with Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged Disease or NUP98 Alterations
Study Type: Treatment
Phase: I
NCTID: NCT05886049
Principal Investigator:
Jesus Gonzalez Lugo
The Project: Every Child Protocol: A Registry, Eligibility Screening, Biology and Outcome Study
Study Type: Other
Phase: N/A
NCTID: NCT02402244
Principal Investigator:
Keith August
A Phase 2 Study of Blinatumomab in Combination with Chemotherapy for Infants with Newly Diagnosed Acute Lymphoblastic Leukemia with Randomization of KMT2A-Rearranged Patients to Addition of Venetoclax
Study Type: Treatment
Phase: II
NCTID: NCT06317662
Principal Investigator:
Keith August
A PHASE 1 STUDY OF REVUMENIB, AZACITIDINE, AND VENETOCLAX AND IN PEDIATRIC AND YOUNG ADULT PATIENTS WITH REFRACTORY OR RELAPSED ACUTE MYELOID LEUKEMIA
Study Type: Treatment
Phase: I
NCTID: NCT06177067
Principal Investigator:
Keith August
A Randomized, Multicenter, Phase III Trial of Tacrolimus/Methotrexate/Ruxolitinib versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation GVHD Prophy Rux PROGRESS IV
Study Type: Treatment
Phase: III
NCTID: NCT06615050
Principal Investigator:
Muhammad Umair Mushtaq
A Phase II Study of Inotuzumab Ozogamicin Followed by Blinatumomab for Ph-Negative CD22-Positive B-Lineage Acute Lymphoblastic Leukemia in Newly Diagnosed Older Adults or Adults with Relapsed or Refractory Disease
Study Type: Treatment
Phase: II
NCTID: NCT03739814
Principal Investigator:
Kenneth Byrd
A Randomized Phase II Study Comparing Cytarabine + Daunorubicin 7+3 vs Daunorubicin and Cytarabine Liposome, Cytarabine + Daunorubicin + Venetoclax, Azacitidine + Venetoclax, and Daunorubicin and Cytarabine Liposome + Venetoclax in Patients Aged 59 or Younger Who are Considered High-Risk Adverse Acute Myeloid Leukemia as Determined by MYELOMATCH; A MYELOMATCH CLINICAL TRIAL
Study Type: Treatment
Phase: II
NCTID: NCT05554406
Principal Investigator:
Tara Lin
A Phase 2 Study of Inotuzumab Ozogamicin NSC 772518 in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia B-ALL
Study Type: Treatment
Phase: II
NCTID: NCT02981628
Principal Investigator:
Kevin Ginn
Chronic Health Conditions in Down Syndrome-Associated Acute Leukemia: The Down Syndrome Phenotyping Acute Leukemia Study in Survivors DS-PALS Survivors
Study Type: Other
Phase: N/A
NCTID: NCT05702645
Principal Investigator:
Keith August
A Phase 1 Study of SEA-CD70 Monotherapy or Combination with Azacitideine in Subjects with Myeloid Malignancies
Study Type: Treatment
Phase: I
NCTID: NCT04227847
Principal Investigator:
Abdulraheem Yacoub